Big Data Science with the BD2K-LINCS Data Coordination and Integration Center

Description

In this course, you will :

• The Library of Integrative Network-based Cellular Signatures (LINCS) is an NIH Common Fund program.
• The idea is to perturb different types of human cells with many different types of perturbations such as: drugs and other small molecules; genetic manipulations such as knockdown or overexpression of single genes; manipulation of the extracellular microenvironment conditions
• Then, to better understand the molecular networks that are affected by these perturbations, changes in level of many different variables are measured